Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens BAF chromatin remodeling complex subunit BCL7B (BCL7B), transcript variant 2 (NM_001197244). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q9BQE9 |
| Entry Name | BCL7B_HUMAN |
| Gene Names | BCL7B |
| Alternative Gene Names | |
| Alternative Protein Names | B-cell CLL/lymphoma 7 protein family member B (allergen Hom s 3) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 202 |
| Molecular Weight(Da) | 22195 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASES |
Background
| Function | FUNCTION: Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1 (PubMed:25569233). Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation (PubMed:25569233). May play a role in lung tumor development or progression (By similarity). {ECO:0000250|UniProtKB:Q921K9, ECO:0000269|PubMed:25569233}. |
| Pathway | |
| Protein Families | BCL7 family |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:9860302, ECO:0000269|PubMed:9931421}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |