Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.coli |
| Tag Info | N-terminal GST-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | Q9Y4W6 |
| Gene Names | AFG3L2 |
| Alternative Names | Paraplegin-like protein |
| Expression Region | Partial(550-759aa ) |
| Molecular Weight | 50.8 kDa |
| Protein Sequence | ERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKGLGYAQYLPKEQYLYTKEQLLDRMCMTLGGRVSEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGPRPFAEKSTYEEF |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | ATP-dependent protease which is essential for axonal development. |
| Involvement in Disease | Spinocerebellar ataxia 28 (SCA28); Spastic ataxia 5, autosomal recessive (SPAX5) |
| Subcellular Location | Mitochondrion, Mitochondrion inner membrane, Multi-pass membrane protein |
| Protein Families | AAA ATPase family; Peptidase M41 family |
| Tissue Specificity | AFG3L2 |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |