Specification
| Organism | Homo sapiens (Human) |
| Expression Host | E.coli |
| Tag Info | N-terminal 6xHis-SUMO-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | Q13510 |
| Gene Names | ASAH1 |
| Alternative Names | Acylsphingosine deacylase N-acylsphingosine amidohydrolase Putative 32KDA heart protein Short name:PHP32 |
| Expression Region | Full Length of Mature Protein(22-395aa ) |
| Molecular Weight | 58.7 kDa |
| Protein Sequence | QHAPPWTEDCRKSTYPPSGPTYRGAVPWYTINLDLPPYKRWHELMLDKAPVLKVIVNSLKNMINTFVPSGKIMQVVDEKLPGLLGNFPGPFEEEMKGIAAVTDIPLGEIISFNIFYELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGYVGMLTGFKPGLFSLTLNERFSINGGYLGILEWILGKKDVMWIGFLTRTVLENSTSYEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVYELDAKQGRWYVVQTNYDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMYDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCIGW |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. |
| Involvement in Disease | Farber lipogranulomatosis (FRBRL); Spinal muscular atrophy with progressive myoclonic epilepsy (SMAPME) |
| Subcellular Location | Lysosome |
| Protein Families | Acid ceramidase family |
| Tissue Specificity | ASAH1 |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |