Specification
| Organism | Homo sapiens (Human) |
| Expression Host | Yeast |
| Tag Info | N-terminal 6xHis-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | P08865 |
| Gene Names | RPSA |
| Alternative Names | 37 kDa laminin receptor precursor Short name: 37LRP 37/67 kDa laminin receptor Short name: LRP/LR 67 kDa laminin receptor Short name: 67LR Colon carcinoma laminin-binding protein Laminin receptor 1 Short name: LamR Laminin-binding protein precursor p40 Short name: LBP/p40 Multidrug resistance-associated protein MGr1-Ag NEM/1CHD4 Small ribosomal subunit protein uS2 LAMBR, LAMR1 |
| Expression Region | Full Length of Mature Protein(2-295aa ) |
| Molecular Weight | 34.7 kDa |
| Protein Sequence | SGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAAEKAVTKEEFQGEWTAPAPEFTATQPEVADWSEGVQVPSVPIQQFPTEDWSAQPATEDWSAAPTAQATEWVGATTDWS |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. |
| Involvement in Disease | Asplenia, isolated congenital (ICAS) |
| Subcellular Location | Cell membrane, Cytoplasm, Nucleus |
| Protein Families | Universal ribosomal protein uS2 family |
| Tissue Specificity | RPSA |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |