Specification
| Organism | Bos taurus (Bovine) |
| Expression Host | Yeast |
| Tag Info | N-terminal GST-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | P08037 |
| Gene Names | B4GALT1 |
| Alternative Names | UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1 UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1 |
| Expression Region | Cytoplasmic Domain(1-24aa ) |
| Molecular Weight | 29.5 kDa |
| Protein Sequence | MKFREPLLGGSAAMPGASLQRACR |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix. |
| Involvement in Disease | |
| Subcellular Location | Isoform Long: Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein, Cell membrane, Single-pass type II membrane protein, Cell surface, Cell projection, filopodium, Note=Found in trans cisternae of Golgi, B4GALT1 cell surface expression is regulated by UBE2Q1 (By similarity), SUBCELLULAR LOCATION: Isoform Short: Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein, Note=Found in trans cisternae of Golgi, SUBCELLULAR LOCATION: Processed beta-14-galactosyltransferase 1: Secreted |
| Protein Families | Glycosyltransferase 7 family |
| Tissue Specificity | B4GALT1 |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |