Specification
| Organism | Borna disease virus (strain V) (BDV) |
| Expression Host | in vitro E.coli expression system |
| Tag Info | N-terminal 6xHis-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | P52638 |
| Gene Names | G |
| Alternative Names | gp84 gp94 |
| Expression Region | Extracellular Domain(23-467aa ) |
| Molecular Weight | 54.2 kDa |
| Protein Sequence | FDLQGLSCNTDSTPGLIDLEIRRLCHTPTENVISCEVSYLNHTTISLPAVHTSCLKYHCKTYWGFFGSYSADRIINRYTGTVKGCLNNSAPEDPFECNWFYCCSAITTEICRCSITNVTVAVQTFPPFMYCSFADCSTVSQQELESGKAMLSDGSTLTYTPYILQSEVVNKTLNGTILCNSSSKIVSFDEFRRSYSLTNGSYQSSSINVTCANYTSSCRPRLKRRRRDTQQIEYLVHKLRPTLKDAWEDCEILQSLLLGVFGTGIASASQFLRSWLNHPDIIGYIVNGVGVVWQCHRVNVTFMAWNESTYYPPVDYNGRKYFLNDEGRLQTNTPEARPGLKRVMWFGRYFLGTVGSGVKPRRIRYNKTSHDYHLEEFEASLNMTPQTSIASGHETDPINHAYGTQADLLPYTRSSNITSTDTGSGWVHIGLPSFAFLNPLGWLRD |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Unprocessed envelope protein p57 is thought to be involved in attachment of the virus to its cell surface receptor. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Envelope protein p27 and p29 presumably linked by disulfide bond are the viral type II fusion protein, involved in pH-dependent fusion within early endosomes after internalization of the virion by endocytosis. |
| Involvement in Disease | |
| Subcellular Location | Envelope glycoprotein p57: Host endoplasmic reticulum membrane, Single-pass type I membrane protein, Note=Accumulates in the endoplasmic reticulum when unprocessed, whereas cleaved products reaches cell surface, SUBCELLULAR LOCATION: Envelope glycoprotein p27: Virion, Host cell membrane, Peripheral membrane protein, Note=Appear to be associated with infectious virions, SUBCELLULAR LOCATION: Envelope glycoprotein p29: Virion, Host cell membrane, Single-pass type I membrane protein |
| Protein Families | |
| Tissue Specificity | G |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |