Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens receptor accessory protein 6 (REEP6), transcript variant 2 (NM_138393). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q96HR9 |
| Entry Name | REEP6_HUMAN |
| Gene Names | REEP6 C19orf32 DP1L1 |
| Alternative Gene Names | C19orf32 DP1L1 |
| Alternative Protein Names | Receptor expression-enhancing protein 6 (Polyposis locus protein 1-like 1) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 211 |
| Molecular Weight(Da) | 23418 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MDGLRQRVEHFLEQRNLVTEVLGALEAKTGVEKRYLAAGAVTLLSLYLLFGYGASLLCNLIGFVYPAYASIKAIESPSKDDDTVWLTYWVVYALFGLAEFFSDLLLSWFPFYYVGKCAFLLFCMAPRPWNGALMLYQRVVRPLFLRHHGAVDRIMNDLSGRALDAAAGITRNVLQVLARSRAGITPVAVAGPSTPLEADLKPSQTPQPKDK |
Background
| Function | FUNCTION: Required for correct function and survival of retinal photoreceptors (PubMed:27889058). Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity). {ECO:0000250|UniProtKB:Q9JM62, ECO:0000269|PubMed:27889058}. |
| Pathway | |
| Protein Families | DP1 family |
| Tissue Specificity | Expressed in circumvallate papillae and testis (PubMed:16720576). Expressed in the retina. Isoform 1 is predominantly present in mature optic cups. Isoform 1 expression is confined to the cell body and inner segment of developing rod photoreceptor cells (PubMed:27889058). {ECO:0000269|PubMed:16720576, ECO:0000269|PubMed:27889058}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |