Specification
| Alternative Names | CD69 |
| Uniprot ID | Q07108 |
| Tag | Tag-Free |
| Size | 1 vial contains approximately 5x106 cells in 1 ml |
| Screening Marker | Puromycin |
| Culture Media | F-12K + 10% FBS + 10μg/mL Puromycin |
| Buffer | 35% FBS + 55% F-12K + 10% DMSO |
| Tested Application | Binding assay by FACS and cell based ELISA. |
| Storage | Frozen in liquid nitrogen or stored at -80°C |
Background
| Function | Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. |
| Subcellular Location | Membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. |
| Protein Family | |
| References | CD69 is a direct target of miR-367-3p. PMID: 30015935 The frequency of CD69+ T cells was significantly higher in CD8+ and CD4+ T cells in nasal polyps compared with the peripheral blood of patients with chronic rhinosinusitis. PMID: 29749428 this paper shows that decrease of CD69 levels on TCR Valpha7.2(+)CD4(+) innate-like lymphocytes is associated with impaired cytotoxic functions in chronic hepatitis B virus-infected patients PMID: 28606013 AIM expression in the kidney was associated with urinary protein and decline in kidney function. PMID: 26846784 Higher CD69 expression were less sensitive to bendamustine and is associated with chronic lymphocytic leukemia. PMID: 26701728 |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |