This is a general guide for Polystyrene and PMMA solvent compatibility. Your individual polymer particle solubility should be determined by experiment**, since here are many factors that may affect polymer particle solvent compatibility,
There are five important controls for immunofluorescence: Positive Control; Omitting the Primary Antibody Control; Absorption Control; Isotype Control:Omitting the Secondary Antibody Control
When selecting an isotype control for flow cytometry, it is essential to choose an antibody that matches the primary antibody as closely as possible to ensure accurate data interpretation. Here are the key factors to consider when choosing an isotype control:
Isotype controls are antibodies used as negative controls to help researchers distinguish between specific and non-specific binding in immunoassays. They are particularly important in techniques like flow cytometry and immunohistochemistry, where background staining can be a significant issue.
Current Nanobody/VHH clinical trial; nanobody/VHH therapeutics development status
In the dynamic field of life sciences, nanobody—or Variable Heavy-chain Domain (VHH)—is emerging as a powerful tool for researchers. Derived from the immune systems of camelid species like llamas and alpacas, this small, single-domain antibody offers unique advantages over traditional antibodies.
At Echo Bio, we provide high-quality nanobody products tailored for life science research.
Nanobody, also known as single-domain antibodies or VHHs, are revolutionizing the field of life science research. These unique molecules offer several advantages over traditional antibodies, making them valuable tools for a wide range of applications.
— An extracellular glycoprotein synthesized in the liver and secreted into the blood.
— Controls the activity of vasoactive peptide hormones, growth factors and cytokines by specifically removing C-terminal basic residues such as Arg or Lys.
— A member of the CPN/E subfamily of “regulatory” metallo-carboxypeptidases.
— Circulates in blood plasma as a hetero-tetramer consisting of two 83 kDa (CPN2) domains each flanked by a 48 to 55 kDa catalytic (CPN1) domain.
The 280 kDa form of CPN is a dimer of heterodimers, with each heterodimer containing one catalytic subunit and one 83 kDa subunit.
The 83 kDa protein is a non-catalytic regulatory subunit whereas the 55 kDa and 48 kDa proteins represent the native or proteolytically cleaved forms of the active subunit.
Figure 1.Molecular model of the 83 kDa subunit of CPN. A three-dimensional homology model of the 83 kDa subunit.
Figure 2.Stereo image of the structure of the catalytic subunit of human CPN. The ribbon representation shows the catalytic domain on top and the cylindrical TT domain at the bottom.
Reference:
Echo Biosystems have developed a series of high-quality Human carboxypeptidase N protein antibody to meet your research needs.
| CPN1 Polyclonal Antibody | CPN1 from Yeast | CPN1 from Baculovirus |
| CPN1 from E.coli | CPN1 Mammalian cell | |
| CPN2 from Yeast | CPN12 from Baculovirus | CPN2 from E.coli |
| CPN2 from Mammalian cell |
