Specification
| Organism | Myrmecia pilosula (Jack jumper ant) (Australian jumper ant) |
| Expression Host | Baculovirus |
| Tag Info | N-terminal GST-tagged and C-terminal 6xHis-tagged |
| Purity | Greater than 85% by SDS-PAGE |
| Uniprot ID | P0C023 |
| Gene Names | N/A |
| Alternative Names | DELTA-myrtoxin-Mp1a B chain Short name: Mp1a B chain Pilosin-3 subunit b Short name: Pilosulin-3b |
| Expression Region | Full Length(1-23aa ) |
| Molecular Weight | 30.8 kDa |
| Protein Sequence | LIGLVSKGTCVLVKTVCKKVLKQ |
| Form | Liquid or Lyophilization |
| Buffer | The default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol if the delivery form is liquid. The lyophilization buffer is Tris/PBS-based buffer, 6% Trehalose, pH 8.0 if the delivery form is lyophilized powder. Please contact us if you have any special requirment. |
| Reconstitution | Please reconstitute protein in deionized sterile water and we recommend that briefly centrifuge thevial prior to opening the vial .We recommend aliquot for long-term storage at -20℃/-80℃. |
Background
| Relevance | Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles (PubMed:28513074). Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells, (PubMed:28513074). Shows broad-spectrum activity against a diverse range of bacteria, and cell lines, as well as hemolytic activity (EC(50)=2.18 µM) (PubMed:28513074). In vivo, shows moderate insecticidal activity against D.melanogaster and potent anthelmintic activity against the veterinary nematode H.contortus (PubMed:32629771). In addition, intraplantar injection into mice induces nocifensive behavior and mechanical allodynia (PubMed:28513074). |
| Involvement in Disease | |
| Subcellular Location | |
| Protein Families | |
| Tissue Specificity | N/A |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |