Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens zinc finger HIT-type containing 1 (ZNHIT1) (NM_006349). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | O43257 |
| Entry Name | ZNHI1_HUMAN |
| Gene Names | ZNHIT1 CGBP1 ZNFN4A1 |
| Alternative Gene Names | CGBP1 ZNFN4A1 |
| Alternative Protein Names | Zinc finger HIT domain-containing protein 1 (Cyclin-G1-binding protein 1) (Zinc finger protein subfamily 4A member 1) (p18 Hamlet) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 154 |
| Molecular Weight(Da) | 17536 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MVEKKTSVRSQDPGQRRVLDRAARQRRINRQLEALENDNFQDDPHAGLPQLGKRLPQFDDDADTGKKKKKTRGDHFKLRFRKNFQALLEEQNLSVAEGPNYLTACAGPPSRPQRPFCAVCGFPSPYTCVSCGARYCTVRCLGTHQETRCLKWTV |
Background
| Function | FUNCTION: Seems to play a role in p53-mediated apoptosis induction (PubMed:17380123). Binds to NR1D2 and relieves it of its inhibitory effect on the transcription of APOC3 without affecting its DNA-binding activity (PubMed:17892483). {ECO:0000269|PubMed:17380123, ECO:0000269|PubMed:17892483}. |
| Pathway | |
| Protein Families | ZNHIT1 family |
| Tissue Specificity | Expressed abundantly in liver, but weakly in skeletal muscle, ovary and small intestine. {ECO:0000269|PubMed:17892483}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |