Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens TNF receptor superfamily member 17 (TNFRSF17) (NM_001192). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q02223 |
| Entry Name | TNR17_HUMAN |
| Gene Names | TNFRSF17 BCM BCMA |
| Alternative Gene Names | BCM BCMA |
| Alternative Protein Names | Tumor necrosis factor receptor superfamily member 17 (B-cell maturation protein) (CD antigen CD269) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 184 |
| Molecular Weight(Da) | 20165 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MLQMAGQCSQNEYFDSLLHACIPCQLRCSSNTPPLTCQRYCNASVTNSVKGTNAILWTCLGLSLIISLAVFVLMFLLRKINSEPLKDEFKNTGSGLLGMANIDLEKSRTGDEIILPRGLEYTVEECTCEDCIKSKPKVDSDHCFPLPAMEEGATILVTTKTNDYCKSLPAALSATEIEKSISAR |
Background
| Function | FUNCTION: Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. {ECO:0000269|PubMed:10801128, ECO:0000269|PubMed:10903733, ECO:0000269|PubMed:10973284}. |
| Pathway | |
| Protein Families | |
| Tissue Specificity | Expressed in mature B-cells, but not in T-cells or monocytes. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |