Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens transcription factor 23 (TCF23) (NM_175769). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q7RTU1 |
| Entry Name | TCF23_HUMAN |
| Gene Names | TCF23 BHLHA24 |
| Alternative Gene Names | BHLHA24 |
| Alternative Protein Names | Transcription factor 23 (TCF-23) (Class A basic helix-loop-helix protein 24) (bHLHa24) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 214 |
| Molecular Weight(Da) | 23309 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MSQRKARGPPAMPGVGHSQTQAKARLLPGADRKRSRLSRTRQDPWEERSWSNQRWSRATPGPRGTRAGGLALGRSEASPENAARERSRVRTLRQAFLALQAALPAVPPDTKLSKLDVLVLAASYIAHLTRTLGHELPGPAWPPFLRGLRYLHPLKKWPMRSRLYAGGLGYSDLDSTTASTPSQRTRDAEVGSQVPGEADALLSTTPLSPALGDK |
Background
| Function | FUNCTION: Inhibits E-box-mediated binding and transactivation of bHLH factors. Inhibitory effect is similar to that of ID proteins. Inhibits the formation of TCF3 and MYOD1 homodimers and heterodimers. Lacks DNA binding activity. Seems to play a role in the inhibition of myogenesis (By similarity). {ECO:0000250}. |
| Pathway | |
| Protein Families | |
| Tissue Specificity | Expressed in liver, kidney and spleen. {ECO:0000269|PubMed:14516699}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |