Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens PBX/knotted 1 homeobox 1 (PKNOX1), transcript variant 1 (NM_004571). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | P55347 |
| Entry Name | PKNX1_HUMAN |
| Gene Names | PKNOX1 PREP1 |
| Alternative Gene Names | PREP1 |
| Alternative Protein Names | Homeobox protein PKNOX1 (Homeobox protein PREP-1) (PBX/knotted homeobox 1) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 436 |
| Molecular Weight(Da) | 47607 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSEPDAEGVSPPPVESQTPMDVDKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKEGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTISPQGIVVPASALQQGNVAMATVAGGTVYQPVTVVTPQGQVVTQTLSPGTIRIQNSQLQLQLNQDLSILHQDDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKTAQNRPVQRFWPDSIASGVAQPPPSELTMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEEDAGALAPAHISGLVLENSDSLQ |
Background
| Function | FUNCTION: Activates transcription in the presence of PBX1A and HOXA1. {ECO:0000250|UniProtKB:O70477}. |
| Pathway | |
| Protein Families | TALE/MEIS homeobox family |
| Tissue Specificity | Ubiquitous. Isoform 2 is expressed in all examined tissues except in bone marrow. {ECO:0000269|PubMed:15468914, ECO:0000269|PubMed:9143494}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |