Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens p53 apoptosis effector related to PMP22 (PERP) (NM_022121). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q96FX8 |
| Entry Name | PERP_HUMAN |
| Gene Names | PERP KCP1 KRTCAP1 PIGPC1 THW |
| Alternative Gene Names | KCP1 KRTCAP1 PIGPC1 THW |
| Alternative Protein Names | p53 apoptosis effector related to PMP-22 (Keratinocyte-associated protein 1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 193 |
| Molecular Weight(Da) | 21386 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MIRCGLACERCRWILPLLLLSAIAFDIIALAGRGWLQSSDHGQTSSLWWKCSQEGGGSGSYEEGCQSLMEYAWGRAAAAMLFCGFIILVICFILSFFALCGPQMLVFLRVIGGLLALAAVFQIISLVIYPVKYTQTFTLHANPAVTYIYNWAYGFGWAATIILIGCAFFFCCLPNYEDDLLGNAKPRYFYTSA |
Background
| Function | FUNCTION: Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity). {ECO:0000250}. |
| Pathway | |
| Protein Families | TMEM47 family |
| Tissue Specificity | Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts. {ECO:0000269|PubMed:12752121}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |