Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens modulator of apoptosis 1 (MOAP1) (NM_022151). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q96BY2 |
| Entry Name | MOAP1_HUMAN |
| Gene Names | MOAP1 PNMA4 |
| Alternative Gene Names | PNMA4 |
| Alternative Protein Names | Modulator of apoptosis 1 (MAP-1) (MAP1) (Paraneoplastic antigen Ma4) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 351 |
| Molecular Weight(Da) | 39513 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDENRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDPDNTFLSRLNEFLAGEGMTVGELSRALGHENGSLDPEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGRESPEPGEEEFGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVIAGAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEEALLQAILEGNFT |
Background
| Function | FUNCTION: Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. {ECO:0000269|PubMed:15949439}. |
| Pathway | |
| Protein Families | PNMA family |
| Tissue Specificity | Widely expressed, with high levels in heart and brain. {ECO:0000269|PubMed:19366867}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |