Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens DET1 and DDB1 associated 1 (DDA1) (NM_024050). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q9BW61 |
| Entry Name | DDA1_HUMAN |
| Gene Names | DDA1 C19orf58 PCIA1 |
| Alternative Gene Names | C19orf58 PCIA1 |
| Alternative Protein Names | DET1- and DDB1-associated protein 1 (Placenta cross-immune reaction antigen 1) (PCIA-1) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 102 |
| Molecular Weight(Da) | 11835 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MADFLKGLPVYNKSNFSRFHADSVCKASNRRPSVYLPTREYPSEQIIVTEKTNILLRYLHQQWDKKNAAKKRDQEQVELEGESSAPPRKVARTDSPDMHEDT |
Background
| Function | FUNCTION: Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:17452440, PubMed:28437394, PubMed:28302793, PubMed:31686031, PubMed:31819272). In the DCX complexes, acts as a scaffolding subunit required to stabilize the complex (PubMed:31686031, PubMed:31819272). {ECO:0000269|PubMed:17452440, ECO:0000269|PubMed:28302793, ECO:0000269|PubMed:28437394, ECO:0000269|PubMed:31686031, ECO:0000269|PubMed:31819272}. |
| Pathway | Protein modification; protein ubiquitination. |
| Protein Families | DDA1 family |
| Tissue Specificity |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |