Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens cytochrome b-245 chaperone 1 (CYBC1), transcript variant 2 (NM_001033046). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q9BQA9 |
| Entry Name | CYBC1_HUMAN |
| Gene Names | CYBC1 C17orf62 EROS |
| Alternative Gene Names | C17orf62 EROS |
| Alternative Protein Names | Cytochrome b-245 chaperone 1 (Essential for reactive oxygen species protein) (Eros) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 187 |
| Molecular Weight(Da) | 20774 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MYLQVETRTSSRLHLKRAPGIRSWSLLVGILSIGLAAAYYSGDSLGWKLFYVTGCLFVAVQNLEDWEEAIFDKSTGKVVLKTFSLYKKLLTLFRAGHDQVVVLLHDVRDVSVEEEKVRYFGKGYMVVLRLATGFSHPLTQSAVMGHRSDVEAIAKLITSFLELHCLESPTELSQSSDSEAGDPASQS |
Background
| Function | FUNCTION: Functions as a chaperone necessary for a stable expression of the CYBA and CYBB subunits of the cytochrome b-245 heterodimer (PubMed:30361506). Controls the phagocyte respiratory burst and is essential for innate immunity (By similarity). {ECO:0000250|UniProtKB:Q3TYS2, ECO:0000269|PubMed:30361506}. |
| Pathway | |
| Protein Families | CYBC1 family |
| Tissue Specificity | Highly expressed in macrophages, neutrophils and monocytes. {ECO:0000269|PubMed:28351984}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |