Specification
Description | Recombinant protein from the full-length sequence of Homo sapiens COMM domain containing 10 (COMMD10), transcript variant 1 (NM_016144). |
Organism | Homo sapiens (Human) |
Expression Host | Human Cells |
Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
Purity | Greater than 90% by SDS-PAGE gel |
Uniprot ID | Q9Y6G5 |
Entry Name | COMDA_HUMAN |
Gene Names | COMMD10 HSPC305 PTD002 |
Alternative Gene Names | |
Alternative Protein Names | COMM domain-containing protein 10 |
Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
Length | 202 |
Molecular Weight(Da) | 22966 |
Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MAVPAALILRESPSMKKAVSLINAIDTGRFPRLLTRILQKLHLKAESSFSEEEEEKLQAAFSLEKQDLHLVLETISFILEQAVYHNVKPAALQQQLENIHLRQDKAEAFVNTWSSMGQETVEKFRQRILAPCKLETVGWQLNLQMAHSAQAKLKSPQAVLQLGVNNEDSKSLEKVLVEFSHKELFDFYNKLETIQAQLDSLT |
Background
Function | FUNCTION: May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). {ECO:0000269|PubMed:15799966, ECO:0000305|PubMed:21778237}. |
Pathway | |
Protein Families | |
Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:15799966}. |
QC Data
Note | Please contact us for QC Data |
Product Image (Reference Only) | ![]() |