Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens CDC42 effector protein 2 (CDC42EP2) (NM_006779). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | O14613 |
| Entry Name | BORG1_HUMAN |
| Gene Names | CDC42EP2 BORG1 CEP2 |
| Alternative Gene Names | BORG1 CEP2 |
| Alternative Protein Names | Cdc42 effector protein 2 (Binder of Rho GTPases 1) |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 210 |
| Molecular Weight(Da) | 22484 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MSTKVPIYLKRGSRKGKKEKLRDLLSSDMISPPLGDFRHTIHIGSGGGSDMFGDISFLQGKFHLLPGTMVEGPEEDGTFDLPFQFTRTATVCGRELPDGPSPLLKNAISLPVIGGPQALTLPTAQAPPKPPRLHLETPQPSPQEGGSVDIWRIPETGSPNSGLTPESGAEEPFLSNASSLLSLHVDLGPSILDDVLQIMDQDLDSMQIPT |
Background
| Function | FUNCTION: Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts in a CDC42-dependent manner. {ECO:0000269|PubMed:10490598, ECO:0000269|PubMed:11035016}. |
| Pathway | |
| Protein Families | BORG/CEP family |
| Tissue Specificity | Highly expressed in the heart. Weakly expressed in the pancreas and liver. {ECO:0000269|PubMed:10490598}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |