Specification
| Description | Recombinant protein from the full-length sequence of Homo sapiens chromosome 21 open reading frame 91 (C21orf91), transcript variant 2 (NM_017447). |
| Organism | Homo sapiens (Human) |
| Expression Host | Human Cells |
| Tag Info | His or DYKDDDDK. Please contact us if you need further information or require specific designed tag. |
| Purity | Greater than 90% by SDS-PAGE gel |
| Uniprot ID | Q9NYK6 |
| Entry Name | EURL_HUMAN |
| Gene Names | EURL C21orf14 C21orf38 C21orf91 YG81 |
| Alternative Gene Names | C21orf14 C21orf38 C21orf91 YG81 |
| Alternative Protein Names | Protein EURL homolog |
| Application | Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies; For research & development use only! |
| Buffer | Purified protein formulated in a sterile solution of PBS buffer, pH7.2, without any preservatives |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg) |
| Length | 297 |
| Molecular Weight(Da) | 33948 |
| Protein Sequence | (The sequence of expressed protein may have some variation from the sequence shown below. Please contact us for the exact sequence.) MNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNIEGVPKSDLLHTKSLRGHKDCFEKYHLIANQGCPRSKLSKSTYEEVKTILSKKINWIVQYAQNKDLDSDSECSKNPQHHLFNFRHKPEEKLLPQFDSQVPKYSAKWIDGSAGGISNCTQRILEQRENTDFGLSMLQDSGATLCRNSVLWPHSHNQAQKKEETISSPEANVQTQHPHYSREELNSMTLGEVEQLNAKLLQQIQEVFEELTHQVQEKDSLASQLHVRHVAIEQLLKNCSKLPCLQVGRTGMKSHLPINN |
Background
| Function | FUNCTION: Plays a role in cortical progenitor cell proliferation and differentiation. Promotes dendritic spine development of post-migratory cortical projection neurons by modulating the beta-catenin signaling pathway. {ECO:0000250|UniProtKB:Q9D7G4}. |
| Pathway | |
| Protein Families | EURL family |
| Tissue Specificity | Expressed in the brain (PubMed:27404227). Expressed in cortical cells of the germinal ventricular zone and the cortical plate. Underexpressed in the dorsolateral prefrontal cortex, primary visual cortex and cerebellar cortex compared with Down Syndrome patients (at protein level) (PubMed:27404227). {ECO:0000269|PubMed:27404227}. |
QC Data
| Note | Please contact us for QC Data |
| Product Image (Reference Only) |  |